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严重的慢性阻塞性肺疾病(COLD)所致的急性呼吸衰竭(ARF)常伴有钠和水的代谢障碍,表现为水肿及低钠血症(简称低血钠),其发病机理了解甚少,为此,作者在以往研究的基础上进一步探讨了体内激素异常与ARF时钠、水平衡失调的影响。本文对10例COLD所致ARF伴有水肿的病人进行了研究,全部病人经临床及有关检查排除心、肝、肾、糖尿病及肾上腺机能不全等疾病所致水肿,并按研究方案监护6天,在此期间除常规治疗外,每天经口服或静脉给予钠和钾各90mEq,水2500～3000ml,并每
Severe chronic obstructive pulmonary disease (COLD) -related acute respiratory failure (ARF) is often accompanied by metabolic disorders of sodium and water, manifested as edema and hyponatremia (hyponatremia), the pathogenesis of which is poorly understood To this end, the author based on previous studies to further explore the impact of hormonal abnormalities and ARF sodium and water balance disorders. In this paper, 10 patients with ARF accompanied by edema caused by COLD were studied. All patients were excluded from edema caused by diseases such as heart, liver, kidney, diabetes and adrenal insufficiency by clinical and related tests. They were monitored for 6 days according to the research plan, During this period in addition to conventional treatment, daily by oral or intravenous sodium and potassium 90mEq, water 2500 ~ 3000ml, and each