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目的了解奉化市成人代谢综合征(MS)患病情况及其分布特征。方法采用多阶段分层整群随机抽样方法调查奉化市18岁以上人群600人,分别按照国际糖尿病联盟(IDF)、美国国家胆固醇教育计划成人治疗组第三次报告(NCEP-ATPⅢ)2005年修订版、中华医学会糖尿病学分会(CDS)和2009年IDF、世界心脏联盟(WHF)和国际动脉粥样硬化学会(IAS)等多家组织共同暂定的统一MS定义,分析MS及其各组分代谢异常的患病情况。应用SPSS 17.0进行数据分析。计量资料采用t检验和方差分析进行比较;率的比较采用χ2检验及趋势χ2检验,P<0.05为差异有统计学意义。结果按IDF标准,MS粗患病率为29.83%,标化后为17.46%(男性17.56%,女性23.69%,P=0.000);CDS标准,MS粗患病率为23.50%,标化后为12.86%(男性10.38%,女性15.42%,P=0.008);ATPⅢ标准,MS粗患病率为29.67%,标化后为18.22%(男性16.23%,女性20.75%,P=0.022);2009年统一的标准,MS粗患病率为46.33%,标化后为28.99%(男性27.21%,女性30.73%,P=0.222)。按上述4种诊断标准,MS患病率均随着年龄增长而增高(χ2=27.423,P=0.000;χ2=31.752,P=0.000;χ2=27.414,P=0.000;χ2=35.208,P=0.000)。结论 2009年统一的MS诊断标准较其他三种标准更具公共卫生意义。代谢综合征已成为影响奉化市居民生命和健康的重大公共卫生问题,应开展代谢综合征社区综合防治工作。
Objective To understand the prevalence and distribution of adult metabolic syndrome (MS) in Fenghua City. Methods A multistage stratified cluster random sampling method was used to investigate 600 people over the age of 18 in Fenghua City. They were respectively revised according to the International Association of Diabetes Union (IDF) and the National Cholesterol Education Program Third Report of Adult Treatment Group (NCEP-ATPⅢ) 2005 Version, the Chinese Medical Association Diabetes Branch (CDS) and the 2009 IDF, the World Heart Federation (WHF) and the International Society of Atherosclerosis (IAS) and a number of organizations tentative unified definition of MS, MS and its analysis Sub-metabolic abnormalities prevalence. Apply SPSS 17.0 for data analysis. Measurement data were analyzed by t-test and analysis of variance; rate comparison using χ2 test and trend χ2 test, P <0.05 for the difference was statistically significant. Results According to the IDF standard, the crude prevalence rate of MS was 29.83% and 17.46% (17.56% for males and 23.69% for females, P = 0.000). The standard prevalence of CDS was 23.50% (10.38% for males and 15.42% for females, P = 0.008). The standard prevalence of ATP Ⅲ was 29.67% in MS cases and 18.22% in normal subjects (16.23% in males and 20.75% in females, P = 0.022) According to the uniform standard, the crude prevalence rate of MS was 46.33% and normalized 28.99% (27.21% in men and 30.73% in women, P = 0.222). According to the above four diagnostic criteria, the prevalence of MS increased with age (χ2 = 27.423, P = 0.000; χ2 = 31.752, P = 0.000; χ2 = 27.414, P = 0.000; ). Conclusion The unified diagnostic criteria of MS in 2009 are more public health significance than the other three standards. Metabolic syndrome has become a major public health problem affecting the life and health of residents in Fenghua City. Comprehensive prevention and control of metabolic syndrome community should be carried out.