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目的:分析丽水市学生乙肝病毒(HBV)血清感染状况,为实施对健康人群乙肝疫苗免疫计划和乙肝的防治提供依据。方法:用酶联免疫吸附法(ELISA)进行HBsAg、HBsAb、HBeAg、HBeAb、HBcAb检测。结果:共检测学生血清16105份,HBsAg阳性率为4.92%;HBsAb阳性率为30.64%;病毒感染模式以“大三阳”和“小三阳”为主。其中1~7岁组HBsAg阳性率0.60%;8~13岁组HBsAg阳性率2.11%;14~19岁组HBsAg阳性率4.30%;≥20岁组HBsAg阳性率7.75%(性别χ2=0.671,P>0.05)。结论:乙肝病毒感染率随年龄段降低呈下降趋势,性别与感染不相关。HBsAb阳性率不高。建议加强健康教育预防乙肝传播,对学生进行乙肝疫苗的预防接种和强化免疫。
Objective: To analyze the status of hepatitis B virus (HBV) infection in Lishui City, and to provide evidence for the implementation of hepatitis B vaccine immunization program and prevention and treatment of hepatitis B in healthy population. Methods: HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were detected by enzyme-linked immunosorbent assay (ELISA). Results: A total of 16105 serum samples were detected, the positive rate of HBsAg was 4.92%, the positive rate of HBsAb was 30.64%. The virus infection patterns were mainly “Sanyangyang” and “Xiaosanyangyang”. The HBsAg positive rate was 0.60% in 1-7 years old group, 2.11% in 8-13 years old group, 4.30% in 14-19 years old group, and 7.75% in ≥20 years old group (sex χ2 = 0.671, P > 0.05). Conclusion: The infection rate of hepatitis B is declining with age, sex and infection are not related. HBsAb positive rate is not high. Proposes to strengthen health education to prevent the spread of hepatitis B, hepatitis B vaccination and immunization for students.