论文部分内容阅读
IgA 型肾病系由 IgA 免疫复合物介导的慢性肾小球肾炎,上呼吸道感染特别是扁桃体炎过后常使 IgA 型肾病加重,出现肉限血尿。有人过去发现一些患者咽部、鼻腔和唾液的 IgA 含量增高,多数患者血清 IgA 二聚体或较大的多聚体升高,且扁桃体组织产生 IgA 多聚体的细胞增多。作者为了澄清扁桃体的 IgA 与 IgA 型肾病的关系,用免疫荧光法检查7例 IgA 型肾病的扁桃体中产生 IgA 的细胞、IgA 亚群和 J 链表达
IgA nephropathy is mediated by IgA immune complexes of chronic glomerulonephritis, upper respiratory tract infections, especially after tonsillitis, IgA nephropathy often aggravated, there is meat limited hematuria. It has been found in the past that some patients have increased levels of IgA in the throat, nasal cavity and saliva. Most patients have elevated serum IgA dimers or larger multimers and tonsil tissue produces IgA multimer cells. In order to clarify the relationship between tonsil IgA and IgA nephropathy, immunofluorescence was used to examine IgA-producing cells, IgA subpopulations and J chain expression in tonsil of 7 IgA nephropathy