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目的探讨多发性大动脉炎合并心肌梗死患者的临床特点、冠状动脉病变情况、治疗方法及转归。方法回顾性分析2002年1月至2006年4月我院收治的多发性大动脉炎合并心肌梗死患者的症状、体征、实验室检查结果、冠状动脉造影结果、治疗方法及转归资料。结果本组多发性大动脉炎I型2例,II型1例,III型2例。其中,合并冠状动脉三支病变3例,双支病变1例,单支病变1例。冠状动脉病变多见于左右冠状动脉近段,中段及分支也可受累。3例患者行经皮冠脉成形术(PTCA)加支架植入术后病情好转,1例经药物治疗后仍有胸痛发作,1例于住院期间死亡。结论多发性大动脉炎合并心肌梗死并不少见,受累的冠状动脉病变较重,病死率较高。
Objective To investigate the clinical features, coronary artery disease, treatment and prognosis of patients with polyarteritis and myocardial infarction. Methods The symptoms, signs, laboratory findings, coronary angiography, treatment and outcome data of patients with multiple arteritis with multiple arteritis and myocardial infarction admitted to our hospital from January 2002 to April 2006 were retrospectively analyzed. Results In our study, there were 2 cases of type I polymyositis, 1 case of type II and 2 cases of type III. Among them, three cases of coronary artery disease in 3 cases, 1 case of double-vessel disease, 1 case of single-vessel disease. Coronary artery lesions more common in the proximal coronary artery, the middle and branches may also be involved. Three patients underwent percutaneous transluminal coronary angioplasty (PTCA) plus stenting improved their condition. One patient had chest pain after drug treatment and one patient died during hospitalization. Conclusions Multiple arteritis with myocardial infarction is not uncommon. The affected coronary arteries are severe and the mortality rate is high.