论文部分内容阅读
本文研究了植物中天然存在的邻香豆酸、对香豆酸、咖啡酸和香豆素对SOS诱导和脂质过氧化的体外抑制,对环磷酰胺致小鼠骨髓微核和精子畸形的影响,及其可能的机理。以丝裂霉素C(MMC,40μg/ml)和UV(30w,距离30cm,照射15秒)为阳性物诱导PQ35菌株的SOS反应。抗MMC实
In this paper, the effects of naturally occurring o-coumaric acid, p-coumaric acid, caffeic acid and coumarin on SOS induction and lipid peroxidation in vitro and on the micronuclei and sperm deformity induced by cyclophosphamide in mice bone marrow , And its possible mechanism. The SOS response of the PQ35 strain was induced with mitomycin C (MMC, 40 μg / ml) and UV (30 w, 30 cm distance, irradiation for 15 seconds) as positive. Anti-MMC real