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微量元素硒selenium(Se)在机体内是一种非特异性抗氧化剂;Se是某些重要酶(如谷胱甘肽过氧化酶)的组分之一,这些酶能防止毒性过氧化物在细胞内蓄积。所形成的过氧化物也可被硒蛋氨酸(selenomethionine,为机体内主要含硒氨基酸)分解。维生素E(α-生育酚)也能清除此类过氧化物,Se和VE在药理学上起协同作用。因此可以说Se和VE能够保护细胞膜和微器官膜免于氧化损伤。 1930年发现Se是牛和其他家畜的剧毒物,60年代初期发现Se又是防治动物缺乏病的必需营养成分,如牛、羊、猪和家禽的白肌病、鸡的渗出性素质Exudativediathesis、大鼠的肝坏死以及动物的某
Selenium (Se), a trace element selenium, is a non-specific antioxidant in the body; Se is one of the components of certain important enzymes, such as glutathione peroxidase, which prevent the formation of toxic peroxides in cells Accumulation within. The resulting peroxide can also be selenomethionine (selenomethionine, the body’s main selenium-containing amino acids) decomposition. Vitamin E (alpha-tocopherol) also clears off such peroxides, and Se and VE act synergistically in pharmacology. It can thus be said that Se and VE protect the cell membrane and the micro-organ membrane from oxidative damage. In 1930, Se was found to be a highly toxic substance in cattle and other livestock. In the early 1960s, Se was also found to be an essential nutrient in the prevention and treatment of animal diseases such as white muscle disease in cattle, sheep, pigs and poultry, and exudative diathesis of chickens. Liver necrosis in rats and animals