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应用ELISA方法检测了186例自发性流产患者血清中抗精子抗体（AsAb）、抗子宫内膜抗体（EMAb）与抗弓形虫抗体（ATAb），并以56例正常育龄妇女作为对照。结果表明：反复自发性流产患者血清中AsAb、EMAb、ATAb阳性率分别为29．03％、38．71％和18．82％，而正常对照组的阳性率分别相应为1．79％、3．57％和1．79％（P＜0．01）。ATAb阳性率随流产次数的增加而增加（P＜0．05），AsAb阳性率随流产次数的增加而减少（P＜0．05）。流产时孕期＜90天者血清AsAb阳性率明显高于流产时孕期≥90天者（P＜0．05），EMAb阳性率与流产次数和流产时孕期之间无明显关系。本文结果提示：三种血清抗体ASAb、EMAb、ATAb与反复自发性流产密切相关，可能是造成自发性流产的重要因素，尤其在自发性流产的早期阶段。
Serum antisperm antibody (AsAb), anti-endometrial antibody (EMAb) and anti-toxoplasma antibody (ATAb) were detected in 186 patients with spontaneous abortion by ELISA. 56 normal women of childbearing age were used as controls. The results showed that the positive rates of serum AsAb, EMAb and ATAb in patients with recurrent spontaneous abortion were 29.03%, 38.71% and 18.82% respectively, while the positive rates in normal control group were 1.79%, 3 .57% and 1.79% (P <0.01). The positive rate of ATAb increased with the increase of abortion times (P <0.05), and the positive rate of AsAb decreased with the increase of abortion times (P <0.05). The positive rate of serum AsAb in abortion <90 days was significantly higher than that in miscarriage ≥ 90 days (P <0.05). There was no significant correlation between the positive rate of EMAb and the number of miscarriage and pregnancy during abortion. Our results suggest that the three serum antibodies ASAb, EMAb, ATAb and recurrent spontaneous abortion are closely related may be an important factor in spontaneous abortion, especially in the early stages of spontaneous abortion.