CXB-909 Attenuates Cognitive Deficits in the Mu-P-75 Saporin Mouse Model of Alzheimer’s Disease

• 作 者: Steven Lowrance Jessica Matchy
• 机 构: FieldNeurosciencesInstituteLaboratoryforRestorativeNeurology,PrograminNeuroscience
• 出 处: 神经系统科学与医药(英文)
• 发表日期: 2012年1期
• 关键词: Alzheimer’s Disease Memory Deficits Substituted PYRIMIDINES Mu-p-75 SAPORIN MORR

The purpose of this study was to determine if the substituted pyrimidine, CXB-909 (formerly known as KP544) which has been shown to amplify the effects of nerve growth factor in elevating choline-acetyltransferase activity in vitro, could attenuate memory