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目的研究胎婴儿先天性畸形的发病情况,探讨畸形儿死亡原因。方法回顾分析1970~1997年851例胎婴儿病理解剖材料和临床资料。结果317例胎婴儿患有先天性畸形。尸检畸形检出率为37.3%,畸形儿男女比例为1∶0.81。单发畸形占47.9%、多发畸形占52.1%。心血管系统畸形所占比例最高,其次为泌尿生殖系统、呼吸系统、神经系统及免疫系统。结论胎婴儿主要死亡原因为致死性畸形、感染和缺氧。九十年代与七、八十年代相比,因感染死亡数明显下降,因缺氧死亡比例增加,因畸形致死比例无显著变化
Objective To study the incidence of congenital malformations in infants and explore the causes of malformations. Methods Retrospective analysis of 851 cases of fetus and fetus from 1970 to 1997 pathological anatomy materials and clinical data. Results 317 cases of fetal infants with congenital malformations. The autopsy deformity detection rate was 37.3%, male and female ratio of malformation children was 1:0.81. Single malformations accounted for 47.9%, multiple malformations accounted for 52.1%. Cardiovascular malformations accounted for the highest proportion, followed by genitourinary system, respiratory system, nervous system and immune system. Conclusion The main causes of fetal death are lethal deformity, infection and hypoxia. Compared with those in the 1970s and 1980s, the number of deaths due to infection decreased significantly. The proportion of deaths due to malformations did not change significantly due to the increase in the proportion of deaths due to hypoxia