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利用正交设计试验，优选出制备环孢素脂质体（１）的２个最佳处方，制备出１溶液，以显微镜计数法计算其粒径分布，应用薄层色谱分离法半定量地测定了其包封率（２种处方分别为９１．０％、８６．５％）。在此基础上，制备出１外用制剂。并用高效液相色谱法测定了制剂中环孢素的含量
Orthogonal design test was used to optimize the two best prescriptions for preparation of cyclosporin liposomes (1), and a solution was prepared. The particle size distribution was calculated microscopically and was determined semi-quantitatively by thin-layer chromatography The encapsulation efficiency of the two kinds of prescriptions was 91.0% and 86.5% respectively. On this basis, 1 external preparation was prepared. The contents of cyclosporine in the preparation were determined by high performance liquid chromatography