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目的:观察Supreme喉罩用于老年结直肠癌根治术的麻醉效果。方法:择期行全麻老年结直肠癌根治术53例,随机分为喉罩组(观察组)26例和气管插管组(对照组)27例。采用丙泊酚全凭静脉麻醉,观察比较两组丙泊酚、瑞芬太尼、维库溴铵用量、手术时间、麻醉时间、清醒时间、拔管时间和入室后(T0)、诱导后(T1)、插管(喉罩)即刻(T2)、插管(喉罩)3min(T3)、拔管(喉罩)即刻(T4)、拔管(喉罩)3min(T5)不同时间节点的SBP、DBP、MBP和HR水平变化。结果:观察组丙泊酚和维库溴铵用量均显著少于对照组(P<0.05),瑞芬太尼用量两组比较,差异不显著(P>0.05);苏醒时间和拔管时间均显著早于对照组(P<0.05),手术时间和麻醉时间两组比较,均差异不显著(P>0.05)。观察组T2、T3、T4、T5时间节点的SBP、DBP、MBP和HR水平均显著低于对照组(P<0.05);对照组T2、T3、T4、T5时间节点的SBP、DBP、MBP和HR水平均显著低于T0(P<0.05)。结论:Supreme喉罩应用于老年结直肠癌根治术全身麻醉效果优于气管插管。
Objective: To observe the anesthesia effect of the mask of Supreme laryngeal for radical colorectal cancer in the elderly. Methods: Fifty-three elderly patients with colorectal cancer undergoing general anesthesia were randomly divided into laryngeal mask group (observation group), 26 cases and tracheal intubation group (control group), 27 cases. Propofol was used for total intravenous anesthesia. The levels of propofol, remifentanil, vecuronium, operation time, anesthesia time, awake time, extubation time and post-operative time (T0) (T2), intubation (laryngeal mask) 3min (T3), extubation (T4), extubation (laryngeal mask) 3min (T5) at different time points SBP, DBP, MBP, and HR levels. Results: The dosage of propofol and vecuronium in the observation group was significantly less than that of the control group (P <0.05), while the remifentanil dosage was not significantly different between the two groups (P> 0.05); the recovery time and extubation time (P <0.05). There was no significant difference in operative time and anesthesia time between the two groups (P> 0.05). The levels of SBP, DBP, MBP and HR in observation group at T2, T3, T4 and T5 time points were significantly lower than those in control group (P <0.05) HR levels were significantly lower than T0 (P <0.05). Conclusion: The application of Supreme laryngeal mask in elderly patients with colorectal cancer is better than tracheal intubation in general anesthesia.