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为了解该病手术前后食管内环境的变化,作者使用24小时胃肠动态pH值监测仪对11例贲门癌进行术前一周和术后两周的24小时食管内双探极pH值监测。结果表明,术前存在轻度胃食管酸性返流(pH<4时间比值为2.4%±1.8%),手术加用抗返流术式,术后仍出现较严重的胃食管酸性返流(pH<4时间比值为20.9%±12.7%)。因此认为贲门结构的完整性和食管腹段的存在对抗返流具有重要作用。在胸腔负压环境中,残胃扩张致使胃酸呈增加趋势可能是酸返流的根源。建议重视贲门癌切除术中抗返流术式的设计和术后抗返流药物治疗及生活指导
In order to understand the changes in the esophageal environment before and after surgery, the authors used a 24-hour gastrointestinal dynamic pH monitor to monitor 11 patients with cardia cancer within 24 hours before and two weeks after operation. The results showed that there was mild gastroesophageal acid reflux before surgery (pH<4 time ratio was 2.4%±1.8%), anti-reflux surgery was added after surgery, and serious gastroesophageal acidosis still appeared after operation. Reflow (pH<4 time ratio 20.9%±12.7%). Therefore, it is believed that the integrity of the fontanelle structure and the presence of the esophagus in the abdomen have an important role in fighting against reflux. In the negative pressure environment of the thoracic cavity, the increase of gastric acid due to residual gastric distension may be the source of acid reflux. It is recommended to pay attention to the design of anti-reflux surgery during cardiac cancer resection and postoperative anti-reflux medication and life guidance.