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机体内铁状态强烈影响胃肠道对微量元素如镉的吸收,此因素也影响着其他微量元素的生物利用度。因此,调查了234位年龄在15~17岁男、女青少年全血及血清中铁指示剂与微量元素浓度的关系。铁状态用血清铁蛋白、血清可溶性转铁蛋白受体,及可溶性转铁蛋白受体与血清铁蛋白的比率,调查的微量元素有:全血或血清镉、钴、铜、锌、硒、铷、汞和铅,血清钨、全血镉。结果发现,铁状态与血镉、全血或血清钴或血铜呈负相关,与汞浓度呈正相关。硒与血清可溶性转铁蛋白受体呈正相关。铁与铅的关系是不明确的。血清中相关性弱于全血的,但是在血清和全血中,铁与钴均呈强烈的负相关。仅发现铁与锌、铷或钨间存在偶然或许是假性相关。总之,研究支持先前研究认为的镉、钴和铜的吸收通过类似于铁转运机制的结果,但不能解释铁与汞浓度间的正相关。
Body iron status strongly affects the gastrointestinal tract of trace elements such as cadmium absorption, this factor also affects the bioavailability of other trace elements. Therefore, the relationship between iron indicator and the concentration of trace elements in whole blood and serum of 234 male and female adolescents aged 15-17 years were investigated. Serum iron ferritin, serum soluble transferrin receptor, and soluble transferrin receptor and serum ferritin were used in the iron status. The trace elements investigated were: whole blood or serum cadmium, cobalt, copper, zinc, selenium, rubidium , Mercury and lead, serum tungsten, whole blood cadmium. The results showed that iron status and blood cadmium, whole blood or serum cobalt or blood copper was negatively correlated with the mercury concentration was positively correlated. Selenium and serum soluble transferrin receptor was positively correlated. The relationship between iron and lead is not clear. Serum correlates less than whole blood, but both iron and cobalt show a strong negative correlation in both serum and whole blood. Only occasional or perhaps pseudo-correlations between iron and zinc, rubidium or tungsten were found. In summary, the study supports the previous study that the absorption of cadmium, cobalt and copper through a similar mechanism of iron transport results, but can not explain the positive correlation between iron and mercury concentrations.