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目的:观察不同剂量葛根芩连汤方药饼脐疗治疗小儿湿热型腹泻的临床疗效.方法:选取湿热型腹泻患儿72例,按随机数字表法分为高剂量组和低剂量组,每组36例.两组均给与腹泻常规治疗和脐部贴敷药饼治疗,高剂量组药饼由葛根芩连汤方药粉加水制成,低剂量组药饼由10％葛根芩连汤方药粉+90％辅料(玉米淀粉)加水制成.共治疗3 d,比较两组临床疗效、止泻率、中医症状体征治疗有效率、中医证候评分及安全性指标的差异.结果:治疗后,两组中医证候评分均降低,与本组治疗前差异均有统计学意义(P<0.01),且高剂量组中医证候评分低于低剂量组,组间差异有统计学意义(P<0.05).治疗后,高剂量组临床疗效优于低剂量组,组间差异有统计学意义(P<0.05);高剂量组止泻率高于低剂量组,组间差异有统计学意义(P<0.05).在中医症状体征方面,高剂量组在改善舌苔黄腻、大便次数、水样性便、小便短赤、舌红、肛门红赤、呕吐、肠鸣及腹胀方面的效果优于低剂量组,组间差异有统计学意义(P<0.01).结论:葛根芩连方药饼脐疗治疗小儿湿热型腹泻临床疗效肯定,安全可靠.高剂量药饼脐疗疗效优于低剂量药饼,值得进一步深入研究.“,”Objective: To observe the clinical efficacy of umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang prescription of different dosages in treating damp-heat diarrhea in young children. Methods: Seventy-two kids with diarrhea of damp-heat pattern were recruited and divided into a high-dosage group and a low-dosage group using the random number table method, with 36 cases in each group. They all received conventional antidiarrheal treatment and umbilical application with herbal cakes. However, the herbal cakes for the high-dosage group were made of the mixture of Ge Gen Qin Lian Tang powder and water, and those for the low-dosage group consisted of 10％ Ge Gen Qin Lian Tang powder and 90％ auxiliary materials (corn starch) plus water. The treatment duration was 3 d. The clinical efficacy, antidiarrheal rate, effective rate for symptoms and signs of traditional Chinese medicine (TCM), TCM symptoms score, and safety indicators were compared between the two groups. Results: After the treatment, the TCM symptoms scores dropped significantly in both groups (P<0.01) and were lower in the high-dosage group than in the low-dosage group (P<0.05). The clinical efficacy was more significant in the high-dosage group than in the low-dosage group after the treatment, and the between-group difference was statistically significant (P<0.05); the antidiarrheal rate was markedly higher in the high-dosage group than in the low-dosage group (P<0.05). Regarding the TCM symptoms and signs, the high-dosage group showed better results in improving the greasy and yellowish tongue coating, bowel movement frequency, watery excrement, short and dark urine, red tongue body, red anus, vomiting, bowel sounds, and abdominal bloating compared with the low-dosage group, and the between-group differences were statistically significant (P<0.01). Conclusion: Umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang is safe, reliable, and effective in treating damp-heat diarrhea in young children; the high-dosage herbal cakes produce more significant efficacy than the low-dosage ones and are worth further investigation.