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目的分析肌氨肽苷联合早期针灸及康复治疗对急性脑梗死的临床疗效。方法 160例急性脑梗死患者,随机分成A、B、C、D组,每组40例。四组均采用常规治疗,在常规治疗基础上B组采用肌氨肽苷治疗,C组采用早期针灸联合康复治疗,D组采用肌氨肽苷联合早期针灸及康复治疗,观察分析四组的临床疗效。结果 A组中基本治愈0例,显著进步8例,进步13例,无效19例,临床治疗总有效率52.5%(21/40);B组中基本治愈0例,显著进步7例,进步17例,无效16例,临床治疗总有效率60.0%(24/40);C组中基本治愈0例,显著进步13例,进步13例,无效14例,临床治疗总有效率65.0%(26/40);D组中基本治愈0例,显著进步26例,进步11例,无效3例,临床治疗总有效率92.5%(37/40);D组治疗总有效率显著高于A、B、C组,差异有统计学意义(P<0.05)。治疗1个月后,A、B、C、D组患者的美国国立卫生研究院卒中量表(NIHSS)评分分别为(12.68±4.97)、(12.96±3.95)、(11.45±4.63)、(7.85±4.13)分;D组患者的NIHSS评分显著低于A、B、C组,差异有统计学意义(P<0.05)。治疗期间四组患者均未发生显著的不良反应;肝肾功能、血小板、血尿常规等均未发生显著异常。结论在对急性脑梗死患者进行治疗时,肌氨肽苷联合早期针灸及康复治疗可取得比较显著的临床效果,而且不良反应少,具有临床应用和推广价值。
Objective To analyze the clinical effect of combination of aminoglycoside and early acupuncture and rehabilitation therapy on acute cerebral infarction. Methods One hundred and sixty patients with acute cerebral infarction were randomly divided into A, B, C and D groups, 40 cases in each group. Four groups were treated by conventional therapy. On the basis of routine treatment, B group was treated with muscle aminopeptidyl glycosides, C group was treated with early acupuncture combined with rehabilitation, Group D was treated with muscle Aminopeptidase combined with early acupuncture and rehabilitation therapy, Efficacy. Results In group A, 0 cases were basically cured, 8 cases were significantly improved, 13 cases were improved, 19 cases were ineffective, and the total effective rate was 52.5% (21/40) in group A; 0 cases were basically cured in group B, 7 cases were significantly improved and 17 cases were improved 16 cases were ineffective, and the total effective rate of clinical treatment was 60.0% (24/40). In group C, 0 cases were basically cured, 13 cases were significantly improved, 13 cases were improved, 14 cases were ineffective, and the total effective rate was 65.0% 40). In group D, 0 cases were basically cured, 26 cases were significantly advanced, 11 cases were improved, 3 cases were ineffective, and the total effective rate was 92.5% (37/40) in group D. The total effective rate in group D was significantly higher than that in group A, B, C group, the difference was statistically significant (P <0.05). After 1 month of treatment, the NIHSS scores of patients in groups A, B, C and D were (12.68 ± 4.97), (12.96 ± 3.95), (11.45 ± 4.63), (7.85 ± 4.13). NIHSS scores in group D were significantly lower than those in groups A, B and C (P <0.05). No significant adverse reactions occurred in the four groups of patients during the treatment period; no abnormalities such as liver and kidney function, platelets and hematuria were found. Conclusions In the treatment of patients with acute cerebral infarction, combined with aminoglycoside combined with early acupuncture and rehabilitation can achieve more significant clinical effects and less adverse reactions, which has clinical application and promotion value.