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目的了解急性下呼吸道感染患儿非典型病原体感染情况,为诊断、治疗和预防提供依据。方法急性下呼吸道感染患儿1640例,分为婴儿组302例、幼儿组545例和儿童组793例,检测嗜肺军团菌Ⅰ型(LP1)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(CP)、腺病毒(ADV)、呼吸道合胞病毒(RSV)、甲型流感病毒(INFA)、乙型流感病毒(INFB)和副流感病毒(PIV)的Ig M抗体。结果 MP阳性率55.8%,其感染主要在幼儿组和儿童组。INFB阳性率29.7%,INFA阳性率18.8%,感染主要在婴儿组和幼儿组,年龄增大,阳性检出率呈下降趋势。PIV阳性率18.7%,感染主要在婴儿组和幼儿组。ADV、RSV感染主要在婴儿组。结论检测儿童呼吸道非典型病原体感染情况,可为诊断提供依据,预防抗生素滥用,提高疗效。
Objective To understand the prevalence of atypical pathogens in children with acute lower respiratory tract infection and provide evidence for diagnosis, treatment and prevention. Methods A total of 1640 children with acute lower respiratory tract infection were divided into infants group (302 cases), infants group (545 cases) and children group (793 cases). The detection of Legionella pneumophila LP1, Mycoplasma pneumoniae, IgM antibodies against COX, CP, ADV, RSV, INFA, INFB and PIV . Results The positive rate of MP was 55.8%. The infection was mainly in young children and children. INFB positive rate of 29.7%, INFA positive rate of 18.8%, mainly in infants and young children infected group, age, the positive detection rate showed a downward trend. PIV positive rate of 18.7%, mainly in infants and young children infected group. ADV, RSV infection mainly in infants group. Conclusion Detection of atypical pathogens in children with respiratory tract infection can provide the basis for diagnosis, prevent the abuse of antibiotics, and improve the curative effect.