论文部分内容阅读
目的探讨急性脑梗死(ACI)与胰岛素抵抗(IR)及胰岛素抗体(IAb)水平之间的相关性。方法采用放射免疫法测定34例ACI组,28例ACI恢复期组及30名健康对照者的空腹血胰岛素(INS)、IAb水平,同时检测空腹血糖(FBG)、血脂,计算胰岛素敏感指数(ISI)。结果 ACI组INS、IAb显著高于恢复期组及对照组;ISI较对照组显著降低。结论 ACI患者存在明显IR,血IAb水平亦显著增高,IR及IAb可能参与了ACI的发病过程。
Objective To investigate the relationship between acute cerebral infarction (ACI) and insulin resistance (IR) and insulin antibody (IAb) levels. Methods The levels of fasting insulin (INS) and IAb in 34 ACI patients, 28 ACI convalescent patients and 30 healthy controls were measured by radioimmunoassay. Fasting blood glucose (FBG), lipids, insulin sensitivity index (ISI) ). Results The INS and IAb in ACI group were significantly higher than those in recovery group and control group. ISI was significantly lower than that in control group. Conclusions There is a significant IR in patients with ACI and a significant increase in blood levels of IAb. IR and IAb may be involved in the pathogenesis of ACI.