Correlation Factor Analysis of Retinal Microvascular Changes in Patients With Essential Hypertension

来源 :South China Journal of Cardiology | 被引量 : 0次 | 上传用户:junemeng
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Objectives To investigate cor-relation between retinal microvascular signs and essential hypertension classification. Methods The retinal microvascular signs in patients with essential hypertension were assessed with the indirect biomi-croscopy lens, the direct and the indirect ophthalmo-scopes were used to determine the hypertensive retinopathy grades and retinal arteriosclerosis grades.The rank correlation analysis was used to analysis the correlation these grades with the risk factors con-cerned with hypertension. Results Of 72 cases with essential hypertension, 28 cases complicated with coronary disease, 20 cases diabetes, 41 cases stroke, 17 cases renal malfunction. Varying extent retinal arterioscleroses were found in 71 cases, 1 case with retinal hemorrhage, 2 cases with retina edema, 4 cases with retinal hard exudation, 5 cases with retinal he-morrhage complicated by hard exudation, 2 cases with retinal hemorrhage complicated by hard exudation and cotton wool spot, 1 case with retinal hemorrhage complicated by hard exudation and microaneurysms, 1 case with retinal edema and hard exudation, 1 case with retinal microaneurysms, 1 case with branch retinal vein occlusion. The rank correlation analysis showed that either hypertensive retinopathy grades or retinal arteriosclerosis grades were correlated with risk factor lamination of hypertension (r=0.25 or 0.31, P < 0.05), other correlation factors included age and blood high density lipoprotein concerned about hypertensive retinopathy grades or retinal arterioscle-rosis grades, but other parameters, namely systolic or diastolic pressure, total cholesterol, triglyceride, low density lipoprotein cholesterol, fasting blood glucose, blood urea nitrogen and blood creatinine were not confirmed in this correlation analysis(P > 0.05).Conclusions Either hypertensive retinopathy grade or retinal arteriosclerosis grade is close with the hypertension risk factor lamination, suggesting that the fundus examination of patients with hypertension plays a important part in predicting the incidence of cardiovascular events. Objectives To investigate cor-relation between retinal microvascular signs and essential hypertension classification. Methods The retinal microvascular signs in patients with essential hypertension were assessed with the indirect biomi-croscopy lens, the direct and the indirect ophthalmo-scopes were used to determine the hypertensive retinopathy grades and retinal arteriosclerosis grades. The rank correlation analysis was used to analyze the correlation these grades with the risk factors con-cerned with hypertension. Results Of 72 cases with essential hypertension, 28 cases complicated with coronary disease, 20 cases diabetes, 41 cases stroke , 17 cases of renal malfunction. Varying extent of retinal arterioscleroses were found in 71 cases, 1 case with retinal hemorrhage, 2 cases with retina edema, 4 cases with retinal hard exudation, 5 cases with retinal he-morrhage complicated by hard exudation, 2 cases with retinal hemorrhage complicated by hard exudation and cotton wool spot, 1 case with retinal hemorrhage complicated by hard exudation and microaneurysms, 1 case with retinal edema and hard exudation, 1 case with retinal microaneurysms, 1 case with branch retinal vein occlusion. The rank correlation analysis showed that either hypertensive retinopathy grades or retinal arteriosclerosis grades were correlated with risk other correlation factors included age and blood high density lipoprotein concerned about hypertensive retinopathy grades or retinal arterioscle-rosis grades, but other parameters, namely systolic or diastolic pressure, total cholesterol (r = 0.25 or 0.31, P <0.05) , triglyceride, low density lipoprotein cholesterol, fasting blood glucose, blood urea nitrogen and blood creatinine were not confirmed in this correlation analysis (P> 0.05) .Conclusions Either hypertensive retinopathy grade or retinal arteriosclerosis grade is close with the hypertension risk factor lamination, suggesting that the fundus examination of patientswith hypertension plays a important part in predicting the incidence of cardiovascular events.
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