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苦参碱(Matrine)是从苦参(Sophora flavescens Ait.)等豆科槐属植物中提取的生物碱,具有抗肿瘤、平喘和抑菌作用。临床观察,对急性菌痢有明显的疗效。它是“妇炎栓”的主药。电离常数是酸碱性药物的一个重要参数,有关苦参碱的电离常数仅见用电位滴定法测定的数值。本文报道以间硝基
Matrine is an alkaloid extracted from Sophora flavescens Ait. and other leguminous plants. It has anti-tumor, antiasthmatic, and antibacterial properties. Clinical observation has obvious curative effect on acute bacillary dysentery. It is the main drug of “Fu Yan Shuan”. The ionization constant is an important parameter of the acid-base drug, and the ionization constant of the matrine is only found by potentiometric titration. This article reports inter-nitro