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钙离子(Ca~(++))是心肌、血管平滑肌电兴奋和机械收缩的重要物质,参与细胞代谢的一些关键酶如腺苷酸环化酶、鸟苷酸环化酶、磷酸二酯酶的调节,它与环一磷酸腺苷(cAMP)的作用关系密切。近年来对钙通道、钙调节蛋白、钙通道阻滞剂等的研究,不断取得进展。现将钙对心血管系统作用的研究动态作一概述。 Ca~(++)通道研究的进展 1.通道(Chennel)的概念:生物膜是一种双层脂质和蛋白质镶嵌结构,其中的蛋
Calcium (Ca ~ (++)) is an important substance of electrical and mechanical contraction of myocardium and vascular smooth muscle. Some key enzymes involved in cell metabolism such as adenylate cyclase, guanylate cyclase, phosphodiesterase Regulation, it is closely related to the role of cyclic AMP (cAMP). In recent years, the research on calcium channel, calcium regulatory protein, calcium channel blocker and so on has made continuous progress. The current study on the role of calcium in cardiovascular system is summarized. Advances in Ca ~ (++) channel studies 1. Chennel concept: Biofilm is a bilayered lipid-protein inlay structure in which eggs