论文部分内容阅读
国内广泛使用等容量法对动物进行灌胃给药,本文用对硫磷与硫酸铜做小鼠急性毒性试验,给药方法为低浓高容、高浓低容、浓度一定容量变化三种。结果表明容量加浓度影响受试物的吸收速率,但用等容量法和等浓度法得出的LD_(50)值差异不大。
The domestic widely used isovolumetric method for gavage administration to animals. In this paper, acute toxicity test of parathion and copper sulfate was done. The method of administration was low concentration, high concentration and low volume, and the concentration was changed by a certain amount. The results showed that the capacity and concentration affected the absorption rate of the test substance, but the LD 50 values obtained by the equal volume method and the equal concentration method were not significantly different.