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目的分析低钠血症对肝硬化患者并发症及预后的影响。方法 94例肝硬化并发低钠血症患者,根据其入院时的血钠水平将其分为轻度组(30例),中度组(49例)和重度组(15例)。对比三组患者的并发症、Child-Pugh肝功能分级及死亡率。结果重度组中Child-Pugh C级的占比明显高于中度组和轻度组,且其Child-Pugh评分高于中度组和轻度组(P<0.05);重度组各并发症发生率明显高于中度组和轻度组,而中度组各并发症发病率均高于轻度组,差异具有统计学意义(P<0.05);重度组患者的死亡率为60.0%,均高于中度组的20.4%、轻度组的3.3%,差异具有统计学意义(P<0.05)。结论患者血钠浓度越低,其Child-Pugh评分越高,并发症及并死亡率就越高。肝硬化患者血钠浓度在一定程度上可以反映其肝脏的受损程度,低钠血症程度可作为对肝硬化患者并发症及预后判断的指标。
Objective To analyze the effect of hyponatremia on the complication and prognosis of patients with liver cirrhosis. Methods Ninety - four patients with liver cirrhosis complicated with hyponatremia were divided into mild group (n = 30), moderate group (n = 49) and severe group (n = 15) according to their sodium level at admission. Comparisons were made between three groups of patients with Child-Pugh liver function grading and mortality. Results The proportion of Child-Pugh C grade in severe group was significantly higher than that in moderate group and mild group, and Child-Pugh score was higher than those in moderate group and mild group (P <0.05) (P <0.05). The death rate in severe group was 60.0%, both of which were significantly higher than those in moderate and mild groups 20.4% higher than moderate and 3.3% mild, the difference was statistically significant (P <0.05). Conclusion The lower the serum sodium concentration, the higher the Child-Pugh score, the higher the complications and mortality. The level of serum sodium in patients with cirrhosis can reflect the degree of liver damage to a certain degree. The degree of hyponatremia can be used as an index to judge the complication and prognosis of patients with cirrhosis.