Organotypic hippocampal slices, an emerging tool to model synucleinopathies

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Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. PD has been traditionally considered a motoric disorder characterized by tremor, rigidity and bradykinesia, however it is now settled that PD also comprises a range of non-motor symptoms like hyposmia, sleep disturbances and cognitive impairments (Tysnes and Storstein, 2017).
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