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目的观察山莨菪碱治疗不宁腿综合征 ( RLS)的临床疗效及安全性。方法将 78例随机分两组 ,对照组 38例用阿普唑仑 ,治疗组40例在应用阿普唑仑基础上加用山莨菪碱 ,30天为 1疗程。结果对照组总有效率 6 5 % ,显效率 18% ;治疗组总有效率 93% ,显效率48% ,两组比较有显著性差异 ( P<0 .0 1)。结论山莨菪碱能有效控制 RL S患者症状 ,无明显副作用。
Objective To observe the clinical efficacy and safety of Anisodamine in the treatment of Restless Legs Syndrome (RLS). Methods 78 patients were randomly divided into two groups, the control group of 38 patients with alprazolam, the treatment group 40 patients on the basis of the application of alprazolam anisodamine, 30 days for a course of treatment. Results The total effective rate of the control group was 65% and the markedly effective rate was 18%. The total effective rate was 93% and the effective rate was 48% in the treatment group. There was significant difference between the two groups (P <0.01). Conclusion Anisodamine can effectively control the symptoms of patients with RL S, no obvious side effects.