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目的 对Brugada综合征患者置入治疗性或预防性置入式心脏复律除颤器 (ICD)并评价 1个月临床随访结果。方法 2 1例Brugada综合征 (症状性 9例、无症状性 12例 )于全麻下常规方法置入ICD。每例有Brugada综合征心电图 (ECG)典型改变或钠通道阻滞剂揭示的ECG改变。排除了结构性心脏病并作心脏电生理检查。无症状患者中自发或诱发室性心律失常 8例 ,仅有阳性家族史 4例。结果 置入单腔ICD(VVI) 16台 ,双腔ICD(DDD或DDDR) 5台 (患者伴窦房结功能异常和 或房室传导障碍 )。术中电极除颤器电生理参数符合常规 ,术后无并发症。 1个月后再入院ICD电生理参数检查未改变 ,除颤器内记录无室速和 (或 )室颤触发的拮抗心动过速起搏或电复律、电除颤发生。结论 Brugada综合征患者可安全成功置入ICD ,初期 (1个月 )随访ICD工作良好。
Objective To implant therapeutic or preventive cardioverter-defibrillator (ICD) in patients with Brugada syndrome and to evaluate the clinical follow-up results at 1 month. Method 2 One case of Brugada syndrome (symptomatic in 9 cases, asymptomatic in 12 cases) under general anesthesia ICD. Each case has a typical change in Brugada syndrome electrocardiogram (ECG) or ECG changes revealed by sodium channel blockers. Ruled out structural heart disease and cardiac electrophysiology. Asymptomatic patients, spontaneous or induced ventricular arrhythmia in 8 cases, only 4 cases of positive family history. Results Sixteen single-chamber ICDs (VVI) and five dual-chamber ICDs (DDD or DDDR) were included (patients with sinus node dysfunction or atrioventricular conduction disturbances). Intraoperative electrode defibrillator electrophysiological parameters in line with conventional postoperative complications. One month later, the electrophysiological parameters of the ICD were not changed. The defibrillator recorded no VT and / or ventricular fibrillation, and the antagonistic tachycardia pacing or electrical cardioversion and defibrillation occurred. Conclusion ICD is safe and successful in patients with Brugada syndrome. ICD work well in initial (1 month) follow-up.