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The CAS-MPG Partner Institute for Computational Biology (PICB) is a research institute established by the Max Planck Society of Germany and Chinese Academy of Sciences in 2005.At that time,it is the only institute in the world that is dedicated primarily to the interdisciplinary field of computational biology.The overarching research goal of PICB is to understand and interpret the principal of life using mathematic language.This institute is the fruit of the rich history of scientific collaboration between China and Germany,and reflects the visions of the leading scientists in both countries.