<i>STAT</i>1 gene mutation is not implicated in upper aerodigestive canc

• 作 者: Polat Dura Rene H. M. te Morsc
• 机 构: DepartmentofOtorhinolaryngology,DepartmentsofGastroenterologyandInternalMedicine
• 出 处: 肠胃病学期刊(英文)
• 发表日期: 2012年2期
• 关键词: STAT1 Signal Transducers and ACTIVATORS of Transcription Chronic Mucocutaneous C

Autosomal Dominant Chronic Mucocutaneous Candidiasis (AD-CMC) is characterized by defective T cell immunity, leading to fungal infections limited to mucosal surfaces. Recently it was discovered that mutations in the coiled-coil (CC) domain of STAT1 are th