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全脑全脊髓照射是针对多种癌症的治疗流程中一个重要的组成部分。为了达到最佳的肿瘤控制,需要在靶区体积的确定、重要正常组织的保护、剂量均匀度、射野交接区域以及剂量测定方面都特别注意。本文提出了一种适用于大多数治疗情况的优化了的全脑全脊髓照射治疗技术,以一名因生殖细胞瘤需接受全脑全脊髓照射治疗的17岁男性患者为例,通过综合使用半野衔接技术、扩展半影的射野衔接技术和多叶光拦子野技术,制定临床可实行的治疗计划,大大改善了脊髓靶区内的剂量均匀度,将剂量最大点由处方剂量的124%降低到处方剂量的108%。对仿真人体模进行的实际测量值与计算值的比较表明,测量值和计算值是基本一致的。
Whole-brain whole-spinal irradiation is an important part of the treatment process for many cancers. In order to achieve optimal tumor control, special attention needs to be paid to the determination of target volume, the protection of important normal tissues, uniformity of dose, cross-hatching area and dose determination. In this paper, we propose an optimized whole brain irradiation therapy for most of the treatment situations. Taking a 17-year-old male patient who has undergone whole-brain radiotherapy for germ cell tumors as an example, Convergence technology to expand the penumbral radioshotomy and multi-leaf light block technology to develop a clinically feasible treatment plan, greatly improving the dose uniformity within the spinal cord target area, the maximum dose from the prescribed dose of 124% Reduce to 108% of the prescribed dose. Comparisons of actual measured values and calculated values of the simulated manikin show that the measured values and the calculated values are basically the same.