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通过体外实验观察了当γ干扰素（γｌＦＮ）和肿瘤坏死因子α（ＴＮＦα）作用于ＬＡＫ细胞（淋巴因子激活杀伤细胞）诱导阶段时对ＬＡＫ细胞杀伤涎腺腺样囊性癌细胞系２（ＡＣＣ－２）活性的影响。结果显示：ＴＮＦα可以提高低剂量白介素—２（ｌＬ－２）诱导的ＬＡＫ细胞杀伤活性，且对ＡＣＣ－２的杀伤活性要高于Ｒａｊｉ，增强作用的产生与它对ＬＡＫ细胞增殖的影响无关。γｌＦＮ可以呈剂量依赖性地抑制ＬＡＫ细胞杀伤活性，并轻度抑制ＬＡＫ细胞的增殖
In vitro experiments showed that LAK cells kill the salivary adenoid cystic carcinoma cell line 2 (ACC) when both γ-IFN and TNFα act on the induction phase of LAK cells (lymphokine-activated killer cells) -2) activity. The results showed that TNFα could enhance the killing activity of LAK cells induced by low dose interleukin-2 (IL-2), and its killing activity to ACC-2 was higher than that of Raji. The enhancement effect was not related to its effect on the proliferation of LAK cells. γlFN can inhibit LAK cell killing activity in a dose-dependent manner and mildly inhibit the proliferation of LAK cells