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目的探讨采用欣母沛(卡前列素氨丁三醇注射液)宫体注射预防产后出血的临床效果。方法 140例宫缩乏力性出血高危因素患者,随机分为观察组和对照组,各70例。对照组选择缩宫素进行干预,观察组患者在对照组基础上给予欣母沛宫体注射。观察对比两组产后出血率、产后2 h出血量、产后24 h出血量以及血红蛋白水平。结果观察组患者的产后出血率4.29%(3/70)、产后2 h出血量(74.95±17.62)ml、产后24 h出血量(213.27±157.32)ml以及血红蛋白水平改善情况(1.05±0.29)g/L均优于对照组22.86%(16/70)、产后2 h出血量(117.22±20.99)ml、产后24 h出血量(514.33±212.17)ml、血红蛋白水平(2.02±0.56)g/L,差异均有统计学意义(P<0.05)。结论对宫缩乏力性出血高危因素患者,临床选择宫体注射欣母沛加以预防,可显著降低产后出血率。
Objective To explore the clinical effect of using Xinmaopen (carboprost tromethamine injection) to prevent postpartum hemorrhage. Methods One hundred and forty patients with high risk of uterine bleeding were randomly divided into observation group and control group, with 70 cases in each group. Control group choose oxytocin intervention, observation group patients in the control group on the basis of Ximin Pei Palace injection. The incidence of postpartum hemorrhage, postpartum hemorrhage 2 h, postpartum hemorrhage 24 h and hemoglobin level were observed and compared. Results The postpartum hemorrhage rate in observation group was 4.29% (3/70), the amount of bleeding at 2 h postpartum (74.95 ± 17.62) ml, the amount of hemorrhage at 24 h postpartum (213.27 ± 157.32) ml and the improvement of hemoglobin level (1.05 ± 0.29) g / L were superior to those in control group (22.86%, 16/70), postpartum hemorrhage volume at 2 h (117.22 ± 20.99) ml, postpartum hemorrhage volume at 24 h (514.33 ± 212.17) ml and hemoglobin level (2.02 ± 0.56) The differences were statistically significant (P <0.05). Conclusion In patients with high risk factors for uterine bleeding, the clinical choice of injection of Xinmi Pei Palace to prevent, can significantly reduce the rate of postpartum hemorrhage.