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1987年我们报导了女性痤疮患者血清睾酮水平明显高于正常对照组;男性患者血清雌二醇水平高于正常对照组。同时观察到大部分女性患者伴有不同程度的月经周期紊乱及轻度多毛现象;约三分之一的男性患者胡须生长较晚且稀。为深入评价这些临床异常表现,我们从1987年11月~1989年7月随机分析门诊300例女性患者的月经周期、乳房发育及体毛生长情况,100例男性患者的体毛生长情况,并与150例正常人对照,其结果报告如下。 调查对象与方法 调查对象:寻常型痤疮患者共400例,女性300例,年龄16~34岁,病程2个月~8年;
In 1987, we reported that serum testosterone levels were significantly higher in female acne patients than in normal controls; serum estradiol levels were higher in male patients than in normal controls. Most women were also observed with varying degrees of menstrual cycle disorders and mild hairy phenomenon; about one-third of male beard grow late and thin. To further evaluate these clinical abnormalities, we randomly analyzed the menstrual cycle, breast development and body hair growth in 300 outpatients and body hair growth in 100 male patients from November 1987 to July 1989 and compared with 150 cases Normal control, the results reported below. Subjects and Methods Survey: 400 cases of acne vulgaris patients, 300 women, aged 16 to 34 years, duration of 2 months to 8 years;