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目的探讨甘精胰岛素联合阿卡波糖治疗2型糖尿病患者的可行性。方法回顾性分析我院2006年9月至2009年6月64例口服降糖药失效的2型糖尿病患者应用甘精胰岛素与阿卡波糖联合治疗方案的临床资料。结果 64例患者中60例最终改为甘精胰岛素加阿卡波糖联合治疗方案获得满意血糖控制,另4例应用该方案后血糖控制仍不佳,最终改用强化治疗方案。60例患者在用甘精胰岛素加阿卡波糖方案期间从未出现低血糖。结论甘精胰岛素与阿卡波糖联合治疗的方案对于口服疗效不佳的2型糖尿病患者是一种安全、有效且方便的治疗方案,血糖控制良好,低血糖发生的可能性极小,体重明显降低。
Objective To investigate the feasibility of combining insulin glargine and acarbose in patients with type 2 diabetes mellitus. Methods A retrospective analysis of our hospital from September 2006 to June 2009 64 cases of oral hypoglycemic agents in type 2 diabetes patients with glargine and acarbose combination treatment of clinical data. Results Of the 64 patients, 60 patients eventually switched to glargine plus acarbose combination therapy to achieve satisfactory blood glucose control. The other 4 patients were still not good in their glycemic control after using this regimen, and eventually switched to intensive treatment. Sixty patients had never developed hypoglycemia during the insulin glargine plus acarbose regimen. Conclusions The combination of insulin glargine and acarbose is a safe, effective and convenient treatment for patients with type 2 diabetes who have poor oral response. Good glycemic control, minimal hypoglycemia and significant body weight reduce.