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目的 :观察蚓激酶治疗脑梗死的疗效。方法 :蚓激酶组 4 0例 (男性 2 2例 ,女性 18例 ,年龄 60a±s 12a) ,予蚓激酶 4 60mg ,po ,tid。对照组 4 0例 (男性 2 1例 ,女性 19例 ,年龄 60a± 10a) ,予右旋糖酐 4 0 ,50 0mL加川芎嗪 80mg ,iv ,drip ,qd。疗程均为 2 1d。结果 :蚓激酶组基本治愈率 38% ,总有效率 90 % ,对照组 15%及 73% ,差异有显著意义(P <0 .0 5) ;蚓激酶组治疗后血液流变学各指标及三酰甘油明显降低 ,梗死面积明显缩小 (均P <0 .0 1) ,与对照组比较差异有非常显著意义 (P <0 .0 1)。结论 :蚓激酶对脑梗死有较好疗效。
Objective: To observe the efficacy of lumbrokinase in the treatment of cerebral infarction. Methods: 40 cases of lumbrokinase group (22 males and 18 females, age 60a ± s 12a), lumbrokinase 4 60mg, po, tid. Control group, 40 cases (21 males, 19 females, age 60a ± 10a), dextran 40, 50 0mL plus ligustrazine 80mg, iv, drip, qd. Treatment are 2 1d. Results: The basic cure rate of lumbrokinase group was 38%, the total effective rate was 90%, the control group was 15% and 73%, the difference was significant (P <0. 05); lumbrokinase group after treatment of various indicators of hemorheology and Triacylglycerol was significantly reduced, infarct size was significantly reduced (all P <0.01), compared with the control group, the difference was significant (P <0.01). Conclusion: Lumbrokinase has a good curative effect on cerebral infarction.