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目的探讨膀胱癌脑转移(单发)的临床特征及治疗策略。方法回顾性分析1例膀胱癌脑转移(单发)病人的临床资料,结合文献分析该病的诊治及预后。结果显微手术全切肿瘤组织,病理诊断为膀胱移行细胞癌,术后规律行敏感药物局部间质化疗及静脉全身化疗,术后9个月患者死亡。结论膀胱癌很少发生脑转移,未接受过全身化疗的孤立脑转移瘤患者更为罕见,显微外科手术联合敏感药物局部间质化疗及静脉全身化疗是治疗膀胱癌脑转移(单发)患者的一种安全有效的方法。
Objective To investigate the clinical characteristics and treatment strategies of bladder cancer with brain metastasis (single). Methods A retrospective analysis of 1 case of bladder cancer patients with brain metastases (single) clinical data, combined with the literature analysis of the diagnosis and treatment of the disease and prognosis. Results Microsurgery completely excised the tumor tissue. The pathological diagnosis was bladder transitional cell carcinoma. Localized interstitial chemotherapy and intravenous systemic chemotherapy were performed after the operation. Patients died at 9 months after operation. CONCLUSIONS: Bladder cancer is rare in patients with brain metastases. Patients with isolated brain metastases who have not undergone systemic chemotherapy are more uncommon. Microsurgery combined with sensitized drug local mesenchymal chemotherapy and intravenous systemic chemotherapy is the treatment of patients with brain metastases of bladder cancer (single) A safe and effective method.