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目的观察氨溴索雾化吸入联合阿奇霉素治疗儿童下呼吸道感染的临床疗效。方法选取2011年11月-2014年4月医院下呼吸道感染患儿118例,随机分为治疗组58例和对照组60例,对照组给予阿奇霉素8~10mg·kg-1·d-1加入5%葡萄糖注射液中静脉滴注,1次/d;治疗组在对照组基础上给予盐酸氨溴索7.5mg融入20ml 0.9%氯化钠溶液中超声雾化吸入。比较2组的临床效果。结果治疗组显效率和总有效率为41.4%和96.6%分别高于对照组的30.0%和81.7%;差异有统计学意义(P<0.05)。结论氨溴索雾化吸入联合阿奇霉素治疗儿童下呼吸道感染见效快,使用安全,值得推广应用。
Objective To observe the clinical efficacy of ambroxol inhalation combined with azithromycin in the treatment of children with lower respiratory tract infection. Methods 118 children with lower respiratory tract infection in hospital from November 2011 to April 2014 were randomly divided into treatment group (58 cases) and control group (60 cases). The control group was treated with azithromycin (8-10 mg · kg-1 · d-1) % Glucose injection intravenously, once / d; the treatment group on the basis of the control group given ambroxol hydrochloride 7.5mg dissolved in 20ml 0.9% sodium chloride solution by ultrasonic atomization inhalation. The clinical effects of two groups were compared. Results The effective rate and total effective rate of the treatment group were 41.4% and 96.6%, respectively, which were higher than those of the control group (30.0% and 81.7%, respectively). The difference was statistically significant (P <0.05). Conclusion Ambroxol inhalation combined with azithromycin in children with lower respiratory tract infection effective, safe to use, it is worth promoting the application.