Immunogenicity and immunizing protection effect of GAMA gene DNA vaccine on Plasmodium berghei

• 作 者: Feng Du Si Wang Chen Zhao Ya-M
• 机 构: DepartmentofPathogenBiology,InspectionInstituteofJilinMedicalCollege,DepartmentofImmunology
• 出 处: 亚太热带医药杂志：英文版
• 发表日期: 2016年2期
• 关键词: MALARIA VACCINE DNA VACCINE MULTI-STAGE VACCINE GAMA PLASMODIUM BERGHEI Malaria
• 基金项目: supported by National Natural Science Foundation of China(NSFC)(No.81471978)

Objective: To explore the effect of immunogenicity and immunizing protection of GAMA gene DNA vaccine, which was related with merozoite, ookinete and sporozoite invasion. Methods:Gene fragments were obtained using PCR technique and eukaryotic expression v