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目的探讨桥本甲状腺炎(hashimoto thyroiditis,HT)超声图像分型与甲状腺生化指标(TSH、TT_3、TT_4、FT_3、FT_4、TGA、TMA)之间的相关性。方法采用二维彩色多普勒超声诊断仪(探头频率为10MHz,分辨率为1~2mm)对2014年12月-2016年1月期间我院外科收治的150例经病理确诊合并甲状腺占位性病变的HT住院患者进行超声检查,在超声检查的同时,对所有患者进行甲状腺功能生化指标促甲状腺激素(TSH)、三碘甲状腺原氨酸(TT_3)、四碘甲状腺原氨酸(TT_4)、游离三碘甲状腺原氨酸(FT_3)、游离四碘甲状腺原氨酸(FT_4)、甲状腺微粒体抗体(TGA)、甲状腺球蛋白抗体(TMA)的检查;根据超声图像表现,对HT进行超声分型,将HT各超声分型与甲状腺功能指标检测结果进行对比,探讨两者之间的相关性。结果根据超声图像表现,将HT分为:腺体粗糙型、弥漫散在小结节型、弥漫中结节型、弥漫回声减低型、大片状回声减低型及散在大结节伴腺体回声减低型6型;弥漫回声减低型HT患者的TGA、TMA阳性率最低,弥漫中结节型TGA、TMA阳性率最高;FT_3、FT_4、TT_4仅有少数病例降低,TT_3均在正常范围。结论 HT患者各超声分型与其相关甲状腺生化指标具有密切关系,其可用于HT病程各时期的判断指标。
Objective To investigate the correlation between ultrasound image typing of Hashimoto thyroiditis (HT) and thyroid biochemical indicators (TSH, TT_3, TT_4, FT_3, FT_4, TGA and TMA). Methods Two-dimensional color Doppler ultrasound diagnostic apparatus (probe frequency of 10MHz, resolution of 1 ~ 2mm) from December 2014 to January 2016 in our hospital surgical treatment of 150 cases of pathologically confirmed thyroid gland mass Thirty patients with HT were enrolled in the study. Thyroid hormone (TSH), triiodothyronine (TT_3), tetrathionine (TT_4), thyroid hormone Free triiodothyronine (FT_3), free tetraethionine (FT_4), thyroid microsomal antibody (TGA) and thyroglobulin antibody (TMA). According to the ultrasound image, Type, the HT ultrasound and thyroid function test results were compared to explore the correlation between the two. Results According to the ultrasound images, HT was divided into: glandular rough type, diffuse scattered nodules, diffuse nodules, diffuse echogenic reduction, large echogenic reduction and scattered nodules with gland echo reduction Type 6; the positive rate of TGA and TMA in patients with diffuse echogenic HT was the lowest, while the positive rate of TGA and TMA in diffuse middle nodules was the highest; only a few cases of FT_3, FT_4 and TT_4 were reduced, and TT_3 were in the normal range. Conclusions Each ultrasound type of HT patients is closely related to its related thyroid biochemical indexes, which can be used to judge the indexes of HT in different periods.