Thymosin β4 Impeded Murine Stem Cell Proliferation with an Intact Cardiovascular Differentiation

• 作 者: 聂丽 高仕君 赵亚楠 Jacob Masika 骆红艳 胡新
• 机 构: DepartmentofPhysiology,SchoolofBasicMedicine,nstituteofBrainResearch,CollegeofPharmacy,DepartmentofM
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2016年3期
• 关键词: 小鼠胚胎干细胞 增殖分化 心血管 胸腺肽 β-catenin ESCS STAT3 自我更新能力 thymosin β4 murine embryonic st
• 基金项目: supposed by grants from National Natural Science Foundation of China（No.81100818,No.31100828 and No.81070342）, the Fundamental Research Funds for the Central Universities（HUST：No.2012TS036）

Thymosin β4(Tβ4) is a key factor in cardiac development, growth, disease, epicardial integrity, blood vessel formation and has cardio-protective properties. However, its role in murine embryonic stem cells(m ESCs) proliferation and cardiovascular differen