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目的探讨神经内镜下经鼻蝶微创手术治疗垂体瘤的临床效果。方法回顾性分析20例神经内镜下经鼻蝶手术治疗垂体瘤患者的临床资料。结果随访1年,术后患者催乳素(PRL)为(27.0±31.4)ng/ml,平均下降幅度为(45.6±92.7)ng/ml。肿瘤全切17例,次全切3例;术中出血量为(47.3±11.8)ml,住院时间为(6.9±1.1)d;术后并发症发生率为20.0%(4/20),复发率为15.0%(3/20)。结论内镜下经鼻蝶微创手术治疗垂体瘤的临床疗效显著,是一种安全、有效的治疗方法 ,可作为垂体瘤的首选疗法。
Objective To investigate the clinical effect of endoscopic minimally invasive transnasal surgery for pituitary tumors. Methods A retrospective analysis of 20 cases of endoscopic transnasal surgery in patients with pituitary tumor clinical data. Results One year follow-up, the average PRL was (27.0 ± 31.4) ng / ml and the average decrease was (45.6 ± 92.7) ng / ml. Totally 17 cases were resected and 3 cases were subtotally resected. The blood loss was (47.3 ± 11.8) ml and the hospital stay was (6.9 ± 1.1) days. The incidence of postoperative complications was 20.0% (4/20) The rate was 15.0% (3/20). Conclusions Endoscopic transnasal minimally invasive surgery for pituitary tumor with significant clinical efficacy, is a safe and effective treatment, can be used as the preferred therapy for pituitary tumors.