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目的:探讨感染性眼内炎导致眼球丧失的相关危险因素。方法:对1993-02/2002-12收治的116例(117眼)感染性眼内炎患者进行回顾分析。结果:21例(21眼)行眼球摘除或眼内容物剜出,发生率为17.9%。其中视力无光感的眼内炎病例中眼球丧失的发生率是80%(P=0.0001,OR=73.6);内源性眼内炎的发生率是45.4%(P=0.0125,OR=4.69);眼球破裂伤的发生率是41.7%(P=0.0031,OR=6.78);女性眼内炎的发生率是35.3%(P=0.002,OR=4.48)。前、后5a眼球摘除或眼内容物剜出的发生率分别是26.5%及11.8%(P =0.040)。结论:眼内炎病例中视力无光感、内源性眼内炎、眼球破裂伤是导致眼球摘除或眼内容物剜出的危险因素。眼球摘除或眼内容物剜出的发生率逐年减少。
Objective: To investigate the related risk factors of eyeball loss caused by infective endophthalmitis. Methods: A retrospective analysis was performed on 116 patients (117 eyes) with infectious endophthalmitis admitted between February 1993 and December 2002. Results: Twenty-one eyes (21 eyes) underwent enucleation of the eyeballs or eyeballs. The incidence rate was 17.9%. The incidence of eyeball loss was 80% (P = 0.0001, OR = 73.6) in cases of endophthalmitis with no visual acuity. The incidence of endogenous endophthalmitis was 45.4% (P = 0.0125, OR = 4.69) . The incidence of ocular rupture was 41.7% (P = 0.0031, OR = 6.78). The incidence of endophthalmitis in women was 35.3% (P = 0.002, OR = 4.48). The incidence of enucleation or ocular contents in the first and last 5 years was 26.5% and 11.8%, respectively (P = 0.040). Conclusions: The cases of endophthalmitis have no visual acuity, endogenous endophthalmitis and orbital laceration, which are the risk factors for enucleation of eyeball or eyeball. The incidence of enucleation or ocular contents decreases year by year.