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We describe a 70-year-old female patient with diffuse large B-cell lymphoma of the cerebellum;she received resection of a left atrial myxoma five months ago.To the best of our knowledge,to date no association of atrial myxoma with the malignant cerebellar diffuse large B-cell lymphoma has been reported in the literature,except for high level of interleukin-6 (IL-6) in the serum under both conditions.IL-6 as a pro-inflammatory cytokine has been shown to be associated with tumor progression,including inhibition of cancer cell apoptosis and stimulation of angiogenesis.IL-6 concentrations may provide possible aetiological links between atrial myxoma and cerebellar diffuse large B-cell lymphoma in our case.
We describe a 70-year-old female patient with diffuse large B-cell lymphoma of the cerebellum; she received resection of a left atrial myxoma five months ago. To the best of our knowledge, to date no association of atrial myxoma with the malignant cerebellar diffuse large B-cell lymphoma has been reported in the literature, except for high level of interleukin-6 (IL-6) in the serum under both conditions. IL-6 as a pro-inflammatory cytokine has been shown to be associated with tumor progression, including inhibition of cancer cell apoptosis and stimulation of angiogenesis. IL-6 concentrations may be possible aetiological links between atrial myxoma and cerebellar diffuse large B-cell lymphoma in our case.