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目的:了解脑出血血液循环障碍情况及扩血管药物应用效果。方法:病人共分三级:治疗组119人,于病后4周末始给予扩血管药物等,治疗14天;对照组56人,除不进行扩血管治疗外,其余治疗同治疗组;单纯高血压组78人,常规服用降血压药物。前两组病人于入院后2日内、病后第4周末、病后第6周末共进行3次脑血管血液动力学分析(CBA)、检测,单纯高血压组仅于就诊时查CBA一次。将治疗组CBA指标与单纯高血压级比较,将治疗组治疗前后和对照组同期先后两次CBA各指标差值及两级神经功能缺损平均减少分数(MDSND)相比较,做统计学处理,采用双侧t检验。结果:治疗组与单纯高血压级CBA指标比差异有显著性,治疗组与对照组CBA差值及MDSND相比差异也有显著性。结论:脑出血可造成持久的脑血液循环障碍,而在恢复期给予扩血管药物治疗可显著改善脑血液循环并提高疗效且无明显副反应。
Objective: To understand the situation of cerebral hemorrhage and blood circulation disorders and vasodilator drugs. Methods: The patients were divided into three groups: 119 in the treatment group and vasodilator drugs at the end of the 4th week after the illness for 14 days. In the control group, 56 patients were treated with vasodilator, 78 were in the blood pressure group, taking the antihypertensive drugs routinely. The first two groups of patients within 3 days after admission, 4 weeks after the illness, the first 6 weeks after the disease were carried out 3 times cerebral vascular hemodynamic analysis (CBA), detection, hypertension only check CBA visit once. The treatment group CBA index compared with simple hypertension, the treatment group before and after treatment and the control group had twice the CBA index difference and two-stage neurological deficit reduction score (MDSND) compared to do statistics, using Bilateral t test. Results: There was significant difference between the treatment group and the simple hypertension grade CBA index, the difference between the CBA difference and the MDSND in the treatment group and the control group was also significant. CONCLUSIONS: Intracerebral hemorrhage can cause long-lasting cerebral blood circulation disorders. However, vasodilator drug therapy during convalescence can significantly improve cerebral blood circulation and improve efficacy with no apparent side effects.