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目的:探究盐酸氨溴索对慢性阻塞性肺疾病患者急性期血清白细胞介素8及白细胞介素18的影响价值。方法:选取我院2016年4月-2016年12月慢性阻塞性肺疾病急性期患者88例根据数字随机表分对照组、干预组各44例。对照组实施常规采用常规药物进行治疗;干预组在对照组基础上给予盐酸氨溴索治疗。比较两组患者慢性阻塞性肺疾病治疗效果;护理后血清白细胞介素8及白细胞介素18;住院时间。结果:干预组患者慢性阻塞性肺疾病治疗效果比对照组高,P<0.05;干预组护理后血清白细胞介素8及白细胞介素18比对照组好,P<0.05;干预组住院时间比对照组短,P<0.05。结论:盐酸氨溴索对慢性阻塞性肺疾病患者急性期治疗效果确切,可降低血清白细胞介素8及白细胞介素18水平,缩短住院时间,值得推广。
Objective: To investigate the effect of ambroxol hydrochloride on serum interleukin-8 and interleukin-18 levels in patients with chronic obstructive pulmonary disease in acute phase. Methods: A total of 88 patients with chronic obstructive pulmonary disease (COPD) in our hospital from April 2016 to December 2016 were selected according to the randomized control group and 44 patients in the intervention group. The control group was routinely treated with conventional drugs. The intervention group was treated with ambroxol hydrochloride on the basis of the control group. The treatment effect of chronic obstructive pulmonary disease was compared between the two groups. The levels of serum interleukin-8 and interleukin-18 after nursing were also calculated. Results: The therapeutic effect of chronic obstructive pulmonary disease in the intervention group was higher than that of the control group (P <0.05). The levels of serum interleukin-8 and interleukin-18 in the intervention group were better than those in the control group (P <0.05) Group short, P <0.05. Conclusion: Ambroxol hydrochloride has an exact effect on patients with chronic obstructive pulmonary disease in the acute phase, which can reduce the levels of serum interleukin-8 and interleukin-18 and shorten the hospital stay, which is worth promoting.