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目的探讨精液常规参数对宫腔内人工授精(IUI)临床妊娠率的影响。方法回顾分析125例患者的178个IUI治疗周期,检测记录每个周期患者精液常规参数,并根据妊娠结果分成两组:妊娠组与非妊娠组。对主要精液常规参数精子密度、精子形态及精子总数与IUI临床妊娠率的关系进行分析。结果 125例患者IUI治疗178个周期,临床妊娠34个周期,周期妊娠率为19.10%(34/178),IUI治疗累计临床妊娠率为27.20%(34/125)。妊娠组与非妊娠组精液常规参数无明显差别;精子总数<100×106或精子密度<20×106/ml患者临床妊娠率明显降低(P<0.05)。精子形态对IUI临床妊娠率无影响。结论不孕夫妇进行IUI治疗,当精子总数≥100×106或精子密度≥20×106/ml时才有可能获得较为理想的临床妊娠率。
Objective To investigate the effect of routine parameters of sperm on intrauterine insemination (IUI) clinical pregnancy rate. Methods A retrospective analysis of 125 IUI treatment cycles in 125 patients was performed. The routine parameters of semen in each cycle were recorded and divided into two groups according to the results of pregnancy: pregnancy group and non-pregnancy group. The relationship between sperm density, sperm morphology, sperm count and clinical pregnancy rate of IUI were analyzed. Results 125 cases of IUI treatment 178 cycles, clinical pregnancy 34 cycles, cycle pregnancy rate was 19.10% (34/178), IUI treatment cumulative clinical pregnancy rate was 27.20% (34/125). Pregnancy group and non-pregnant group semen no significant difference in the conventional parameters; sperm total <100 × 106 or sperm density <20 × 106 / ml clinical pregnancy rate was significantly lower (P <0.05). Sperm morphology had no effect on IUI clinical pregnancy rate. Conclusion Infertility couples should be treated with IUI. When the total number of spermatozoa is ≥100 × 106 or the sperm density is ≥20 × 106 / ml, it is possible to get a better clinical pregnancy rate.