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美沙酮（ｍｅｔｈａｄｏｎｅ）通常可用于治疗阿片的成瘾性，研究采用随机双盲法对比了中等剂量与高剂量美沙酮治疗阿片成瘾的疗效。 １９２例阿片成瘾病人随机接受本品一日４０～５０ｍｇ（９７例），８０～１００ｍｇ（９５例）。治疗期间，所有病人均每一周进行１次尿液分析
Methadone is commonly used to treat the addiction of opiates. A randomized double-blind study comparing the effects of moderate and high doses of methadone on opiate addiction was performed. A total of 192 opiate addicts were randomized to receive 40-50 mg (97 cases) and 80-100 mg (95 cases) a day. During treatment, all patients were analyzed urine once per week