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目的 探讨沙美特罗氟替卡松粉吸入剂对慢性阻塞性肺疾病患者肺功能的影响.方法 选取90例慢性阻塞性肺疾病患者为研究对象,依据随机数字表法分为研究组和对照组,每组45例.对照组给予基础治疗,研究组在基础治疗上加用沙美特罗氟替卡松粉吸入剂,观察两组患者的临床疗效和肺活量(FVC)、第1秒用力呼出气体体积(FEV1)、最高呼气流速(PEF)、第1秒用力呼气量和1秒率所占预计值(FEV1/FVC)以及深呼气量(IC)变化.结果 研究组总有效率为86.7％,显著高于对照组的66.7％,差异有统计学意义(P＜0.05).治疗后研究组和对照组的FVC、FEV1、PEF、FEV1/FVC、IC较治疗前均有不同程度改善,且研究组优于对照组,差异有统计学意义(P＜0.05).结论 慢性阻塞性肺疾病患者在基础治疗上给予沙美特罗氟替卡松粉吸入剂治疗效果显著,能较好地改善其肺功能,值得临床应用与推广.“,”Objective To investigate the effect of salmeterol and fluticasone powder inhalation treatment on pulmonary function in patients with chronic obstructive pulmonary disease.Methods 90 cases of chronic obstructive pulmonary disease were randomly divided into study group and control group,45 cases each.The control group received basic treatment,while the study group received salmeterol plus fluticasone inhalation in addition to the basic treatment.Changes in lung function was observed.Results The total effective rate of the study group was 86.7％,significantly higher than that of control group (66.7％) (P＜0.05).After treatment,FEV1,PEF,FEV1/FVC,and IC were significantly improved in both study group and control group,when compared with those before treatment (P＜0.05).Conclusion Basic treatment combined with inhalation of fluticasone and salmeterol powder treatment could significantly improve the lung function of patients with chronic obstructive pulmonary disease.