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目的 总结肾盂输尿管癌肉瘤的临床及病理特点。 方法 报告 3例肾盂、输尿管癌肉瘤病例资料。 3例均为女性 ,年龄分别为 4 3、5 7、75岁。均以肉眼血尿或伴有腰痛就诊 ,经影像学检查诊断为肾盂输尿管肿瘤。 结果 2例行患肾、输尿管全长切除和膀胱部分切除术 ,1例行姑息性肿瘤切除术。病理检查发现为同时存在癌与肉瘤成分。 3例患者术后均未行放化疗 ,分别于术后 8个月 ,14个月和 2个月死于肿瘤转移。 结论 此病临床罕见 ,预后极差 ,诊断依靠病理学检查 ,免疫组化对确诊有重要价值 ,病理诊断应与肉瘤样癌相鉴别。
Objective To summarize the clinical and pathological features of ureteropelvic sarcoma. Methods Three cases of renal pelvis and ureteral sarcoma were reported. All 3 patients were female, with ages of 4, 5 and 7 years, respectively. All were with gross hematuria or low back pain treatment, diagnosis of renal pelvis and ureter tumor by imaging examination. Results Two patients were diagnosed as suffering from partial nephrectomy, full ureter resection and partial resection of the bladder. One patient underwent palliative resection of the tumor. Pathological examination revealed the existence of both cancerous and sarcomatoid components. All patients did not receive radiotherapy and chemotherapy after operation, and died of tumor metastasis at 8 months, 14 months and 2 months respectively. Conclusion The disease is clinically rare and the prognosis is extremely poor. Diagnosis depends on pathological examination. Immunohistochemistry has important value in diagnosis. Pathological diagnosis should be differentiated from sarcomatoid carcinoma.