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目的 为了探讨乙型肝炎肝硬变患者的幽门螺杆菌 (HP)的感染情况及临床意义。方法 本文应用微量 14碳 -尿素呼气试验及组织学检查方法对Child -Pugh分级A、B、C组的 80例乙型肝炎肝硬变患者的幽门螺杆菌 (HP)感染情况进行检测。结果 肝硬变患者与对照组比较 ,HP感染率无明显差异 :但随着Child -Pugh分级升高 ,HP的感染率越高 ,ChildC组病人的HP感染阳性率明显高于其他组 ,差异有显著性。结论 在乙型肝炎肝硬变患者 ,HP感染可能与肝硬化的进展有一定的关系
Objective To investigate the prevalence and clinical significance of Helicobacter pylori (HP) infection in patients with hepatitis B cirrhosis. Methods In this study, H.pylori (HP) infection in 80 patients with hepatitis B cirrhosis from Child-Pugh classification groups A, B and C was detected by micro-14 carbon-urea breath test and histological examination. Results Compared with the control group, there was no significant difference in the HP infection rate between the cirrhosis patients and the control group. However, with the increase of Child-Pugh classification, the higher the HP infection rate was, the positive rate of HP infection in ChildC patients was significantly higher than that in the other groups Significance. Conclusions In patients with hepatitis B cirrhosis, HP infection may be related to the progress of cirrhosis