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目的分析雌激素联合甲硝唑治疗萎缩性阴道炎的临床效果。方法选取我院2010年12月-2011年12月间收治的46名萎缩性阴道炎患者作为研究对象,随机分为观察组与对照组,每组患者各23例。对照组采用甲硝锉治疗,观察组采用雌激素联合甲硝唑治疗,对两组患者的临床效果进行分析对比。结果观察组显效14例,有效7例,无效2例,总有效率为91.30%;对照组显效9例,有效6例,无效8例,总有效率为65.22%,两组数据结果比较具有明显差异(P<0.05)。同时,观察组患者无不良反应出现,对照组患者有3例出现下腹坠胀、外阴不适等不良反应。结论雌激素联合甲硝唑治疗萎缩性阴道炎具有良好的临床效果,值得在临床应用上推广。
Objective To analyze the clinical effect of estrogen combined with metronidazole in the treatment of atrophic vaginitis. Methods Forty-six patients with atrophic vaginitis admitted from December 2010 to December 2011 in our hospital were randomly divided into observation group and control group, with 23 cases in each group. The control group was treated with metronidazole filee, the observation group was treated with estrogen combined with metronidazole, the clinical effect of the two groups were analyzed and compared. Results In the observation group, 14 cases were markedly effective, 7 cases were effective, 2 cases were ineffective, and the total effective rate was 91.30%. In the control group, 9 cases were markedly effective, 6 cases were effective and 8 cases were ineffective. The total effective rate was 65.22%. Difference (P <0.05). At the same time, patients in the observation group showed no adverse reactions. In the control group, there were 3 cases of adverse reactions such as abdominal bulge and vulvar discomfort. Conclusion Estrogen combined with metronidazole treatment of atrophic vaginitis has a good clinical effect, it is worth in the clinical application of promotion.